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. 2020 Jan 13;13(1):dmm043281. doi: 10.1242/dmm.043281

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© 2020. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — Nonsense-mediated decay (NMD) and read-through analysis in McArdle myotubes. (A-C) PYGM mRNA levels in WT and McArdle mouse myotubes after 72 h treatment with different concentrations of amlexanox (AML) (A), Ataluren (ATL) (B) and G418 (C), respectively. (D-F) GP-M protein levels in WT and McArdle mouse myotubes after 72 h treatment with different concentrations of AML (D), ATL (E) and G418 (F), respectively. Black arrows mark the specific PYGM protein band (94 kDa); blue arrows mark unspecific protein bands.