Fig. 8.
Reporter expression is activated in ALS and cone dystrophy zebrafish disease models. (A) Representative images showing that embryos injected with gnat2:OPN1MWW177R mutant opsin have elevated 5XATF6RE:d2GFP expression in photoreceptors, which is absent in injection control embryos injected with all components except the overexpression construct. (B) Representative images showing overlap of hsp70:DsRed and 5XATF6RE:d2GFP expression in sod1 G93R mutant spinal cord, which is absent in WT sod1 control spinal cord. Scale bars: 0.02 mm (A); 0.1 mm (B).