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. 2020 Jan 10;117(4):2076–2083. doi: 10.1073/pnas.1914267117

Fig. 3.

Fig. 3.

Fasted-state gluconeogenesis and AMPK activation. (A and B) PTT on Atp7b−/− and WT mice. (B) Western blot analysis of hepatic AMPK and p-AMPK levels in chow-fed 6-mo-old WT and Atp7b−/− mice. (C) Hepatic gluconeogenic and (D) lipogenic gene mRNA expression measured by real-time PCR analysis. (A and B) *P < 0.05, Atp7b−/− vs. WT diet-matched control, two-way ANOVA, and Sidak’s post hoc test. n = 4 to 11/group. (D and E) *P < 0.05 vs. WT chow; #P < 0.05 vs. WT WD; Student’s t test. n = 5 mice/group.