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. 2020 Jan 10;117(4):2076–2083. doi: 10.1073/pnas.1914267117

Fig. 5.

Fig. 5.

Transcriptomic analysis in Atp7b−/− mice livers. Pathway analysis of transcription factor binding was performed with the significantly changed microarray analysis genes (Fc > 1.5, FDR < 0.05) using the web-based EnrichR platform (27141961). Binding sites identified from ChIP-Seq data within the following down-regulated genes: RXR(NR2B1)_22158963_ChIP-Seq_LIVER_Mouse; LXR(NR1H3)__22158963_ChIP-Seq_LIVER_Mouse; STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse; CEBPa_23403033_ChIPSeq_LIVER_Mouse; PPARa(NR1C1)_22158963_ChIP-Seq_LIVER_Mouse; PXR(NR1I2)_20693526_ChIP-Seq_LIVER_Mouse; GATA1_22025678_ChIP-Seq_K562_Human. *-log10(P value).