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DHEA-S concentration is associated with FEV1PP and suppressed with daily systemic GC use. (A) In subjects with asthma, FEV1PP correlates significantly with DHEA-S levels in both Caucasian men (blue circles; R2 = 0.15; P < 0.001) and women (open red circles; R2 = 0.03; P = 0.047). (B) Chronic daily GC use is associated with DHEA-S suppression in SARP III in men and women.
