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Systemic H84T is very well tolerated in mice. BALB/c mice were injected intraperitoneally with two 50-mg/kg doses of WT, H84T, or D133G BanLec administered 1 mo apart (n = 10 per group). Injection site lesions (A) and appearances (B) were scored, and weight measured (C) for all mice for 59 d postinjection. In C, the data represent the mean for all mice in each group and error bars the SEM.
