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Explanatory diagram of the blood and normal brain kinetic study. Cohorts of study animals were administered (via tail vein) low-dose NaFL, high-dose NaFl, or pegylated-fluorescein (PEG-fluorescein) at 15, 30, 60, or 120 minutes before euthanasia. Blood and tissue specimens were then harvested and used to analyze the presence of different forms of fluorescein in various tissue/blood compartments. fl= fluorescein. Figure is available in color online only.
