Table 1.
Replication of avian bornaviruses in cell cultures
| Virus | Quail | Chicken | Mammalian | Primary | References | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CEC-32 | QM-7 | QT-6 | DF-1 | LMH | VERO | MDCK | C6 | DEF | CEF | QEF | ||
| ABBV-1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | Yes | n/a | n/a | [4] |
| ABBV-2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | Yes | n/a | n/a | [27] |
| CnBV-1 | Yesa | Yes | n/a | Yes | Yes | Nob | n/a | n/a | Yes | n/a | n/a | [28] |
| CnBV-2 | Yes | Yes | n/a | Yes | Yes | Yes | n/a | n/a | Yes | n/a | n/a | [28] |
| CnBV-3 | Yes | Yes | n/a | Yes | Yes | No | n/a | n/a | Yes | n/a | n/a | [28] |
| EsBV-1 | Yes | Yes | n/a | Yes | Yes | Yes | n/a | n/a | Yes | n/a | n/a | [29] |
| PaBV-1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | Yes | No | n/a | [30] |
| PaBV-2 | Yes | Yes | Yes | n/a | Yes | No | No | No | Yes | n/a | n/a | [31–34] |
| PaBV-4 | Yes | Yes | Yes | n/a | n/a | n/a | n/a | n/a | Yes | No | n/a | [30, 33, 34] |
| PaBV-5 | n/a | n/a | No | n/a | n/a | n/a | n/a | n/a | Yes | n/a | No | [35] |
| PaBV-7 | Yes | Yes | n/a | Yes | Yes | No | n/a | n/a | Yes | n/a | n/a | [31] |
aindicates detectable replication in cell line
bindicates no detectable replication in cell line
n/a indicates no data available
DEF Primary duck embryo fibroblasts, CEF Primary chicken embryo fibroblasts, QEF Primary quail embryo fibroblasts, CEC-32 Immortalized quail embryo fibroblasts, QM-7 Immortalized quail smooth muscle cells (derivative of QT-6), QT-6 Immortalized quail fibrosarcoma cells (6 to 24 days old bird), DF-1 Immortalized chicken embryo fibroblasts, LMH Immortalized chicken hepatoma cell line, VERO Immortalized African green monkey kidney cells, MDCK Immortalized Madin-Darby Canine Kidney, C6 Immortalized rat glial cells