Table 39.
Multimodal inpatient treatment for children and adolescents with eating disorders
| Certainty assessment | Impact | Certainty | Importance | ||||||
|---|---|---|---|---|---|---|---|---|---|
| № of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | |||
| Change in Weight (assessed with: Change in BMI from Admit to D/C) | |||||||||
| 2 | Case Series | very serious a | serious b | not serious | not serious | none | One study differentiated between patients with AN-R vs those with AN-B/P or BN and the other differentiated between those with AN-R or AN-B/P and those with BN or EDNOS-B/P. Multimodal treatment was provided in both studies, but varied between studies. Total n = 150 across the two studies. In both studies there was a significantly greater increase in BMI for the group containing AN-R patients (total n = 94). In both studies this group started with a much lower BMI (ie 14.94 and 15.78) and d/c BMI was 19.24 and 19.79. In the group containing only BN and EDNOS-B/P (n = 27) there was no change in BMI during admission. LOS in these studies was 6.25 +/− 2.28 months and 6.8 +/− 3 months. |
⨁◯◯◯ VERY LOW |
CRITICAL |
| very serious a,c | not serious | not serious | serious d | all plausible residual confounding would reduce the demonstrated effect | Study compared EAT-26 at admission to discharge in group of patients with AN-R (n = 33) vs AN-B/P or BN (n = 29). Overall there was a statistically significant improvement in EAT-26 over the course of the admission (p < 0.001). In AN-R groups EAT-26 score decreased from 41.8 (SD 18.56) to 32.17 (SD 22.2) and in AN-B/P or BN group EAT-26 score decreased from 46.67 (SD 15) to 28.83 (SD 14.74). There was no significant difference in change on EAT-26 by diagnosis. LOS was 6.25 +/− 2.28 months. |
⨁◯◯◯ VERY LOW |
IMPORTANT | ||