. 2020 Feb 1;8:4. doi: 10.1186/s40337-020-0277-8

Table 50.

Bright light therapy during CBT-based inpatient treatment versus CBT-based inpatient treatment alone for children and adolescents with anorexia nervosa and major depressive disorder

Certainty assessment	Impact	Certainty	Importance
RCT - Change in Weight (assessed with: Change in BMI per week)
1	randomised trials	serious ^a	not serious	not serious	serious ^b	none	One study randomized patients with AN-R and depressive symptoms (> 17 on HDRS) admitted to CBT-based inpatient treatment to receive either daily 30 min BLT + inpatient treatment (n = 12) × 6 weeks or inpatient treatment only × 6 weeks (n = 12). Patients in both groups had a significant change in their BMI during 6 week study, however change from baseline was statistically significant by week 3 (p = 0.038) in BLT group vs only significant change from baseline at week 6 (p = 0.048) in TAU group.	⨁⨁◯◯ LOW	CRITICAL

Certainty assessment

Impact

Certainty

Importance

№ of studies

Study design

Risk of bias

Inconsistency

Indirectness

Imprecision

Other considerations

RCT - Change in Weight (assessed with: Change in BMI per week)

randomised trials

serious ^a

not serious

serious ^b

none

One study randomized patients with AN-R and depressive symptoms (> 17 on HDRS) admitted to CBT-based inpatient treatment to receive either daily 30 min BLT + inpatient treatment (n = 12) × 6 weeks or inpatient treatment only × 6 weeks (n = 12). Patients in both groups had a significant change in their BMI during 6 week study, however change from baseline was statistically significant by week 3 (p = 0.038) in BLT group vs only significant change from baseline at week 6 (p = 0.048) in TAU group.

⨁⨁◯◯

LOW

CRITICAL

Explanations

^aNo blinding of subjects to treatment group

^bConfidence intervals overlapping with actual size of treatment effect

Bibliography

RCT - Janas-Kozik 2011 [242]