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. 2020 Feb 1;10:3. doi: 10.1186/s13395-020-0221-2

Table 2.

Predictors of ECC-induced strength loss in isolated EDL and anterior crural muscles of mdx mice

ECC:ISO Work Length/angle change Contraction velocity Contraction duration
Ex vivo—(isometric force loss) 0.310 (p < 0.001) 0.563 (p < 0.001) 0.538 (p < 0.001) 0.030 (p = 0.084) 0.455 (p < 0.001)
In vivo—(isometric torque loss) 0.400 (p < 0.001) 0.542 (p < 0.001) 0.780 (p < 0.001) 0.005 (p = 0.606) 0.311 (p < 0.001)

ECC:ISO ratio of maximal eccentric to maximal isometric force

Values = coefficient of determination (R2) following 10 and 70 ECC for ex vivo and in vivo contractions, respectively