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. 2020 Jan 31;16:32. doi: 10.1186/s12917-020-2252-7

Table 4.

Gene expression profiling of pyloric caeca samples by qPCR

Gen category and function Gen symbol Fold changea P-valueb
Lipid uptake and transport
 Fatty acid transporter cd36 1.13 0.175
 Fatty acid transporter fabp2b 1.37 0.004
 Fatty acid transporter fabp2a1 1.11 0.302
 Fatty acid transporter fabp2a2 1.01 0.962
 Fatty acid transporter fatp 0.89 0.120
 Lipoprotein assembly mtp 1.12 0.259
 Lipoprotein component apoB48 1.07 0.730
 Lipoprotein component apoAIV 1.58 0.028
 Lipoprotein component apoAI 1.42 0.001
 Lipid droplet component plin2 0.273 < 0.001
 Nuclear receptor – regular of lipid metabolism pparα 1.52 0.037
 Nuclear receptor – regular of lipid metabolism pparγ 1.38 0.024
 Resynthesis of triacylglycerols mgat2a 1.39 0.023
Phosphatidylcholine synthesis
 Choline transporter slc44a2 1.09 0.329
 Phosphatidylcholine biosynthesis pemt 0.95 0.486
 Phosphatidylcholine biosynthesis chk 0.61 0.068
 Phosphatidylcholine biosynthesis pcyt1a 0.58 0.004
Cholesterol metabolism
 Bile acid nuclear receptor fxr 1.15 0.415
 Cholesterol biosynthesis hmgcr 0.91 0.260
 Cholesterol efflux transporter abca1 0.95 0.650
 Cholesterol efflux transporter abcg5 1.61 0.004
 Cholesterol esterification acat 0.95 0.677
 Cholesterol transporter npc1l1 1.58 < 0.001
 Nuclear receptor - regular of lipid and sterol metabolism lxr 1.06 0.580
 Nuclear receptor - regular of lipid and sterol metabolism srebp1 0.55 0.159
 Nuclear receptor - regular of lipid and sterol metabolism srebp2 1.04 0.907
 Taurine transporter - bile salt metabolism slc6a6 1.39 0.001

aValues are mean fold change observed in the choline diet fed group in comparison with those in the control group

bP-values in bold indicate significant differences between the two treatments; italicized values represent trends