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. 2020 Jan 31;16:32. doi: 10.1186/s12917-020-2252-7

Table 5.

Gene expression profiling of liver samples by qPCR

Gen category and function Gen symbol Fold changea P-valueb
Lipid uptake and transport
 Fatty acid transporter cd36 0.948 0.711
 Fatty acid transporter fatp 0.992 0.923
 Lipoprotein component apo(B100)liver 0.996 0.983
 Lipid droplet component plin2 1.626 0.013
 Nuclear receptor – regular of lipid metabolism pparα 0.660 0.182
 Nuclear receptor – regular of lipid metabolism pparγ 0.973 0.834
Phosphatidylcholine synthesis
 Phosphatidylcholine biosynthesis pemt 0.998 0.988
 Phosphatidylcholine biosynthesis chk 0.505 0.116
 Phosphatidylcholine biosynthesis pcyt1a 0.923 0.597
Cholesterol metabolism abc1a1 0.851 0.310
 Bile acid nuclear receptor fxr 1.154 0.265
 Cholesterol biosynthesis hmgcr 0.936 0.479
 Cholesterol biosynthesis cyp7a1 0.925 0.580
 Cholesterol efflux transporter abca1 0.855 0.289
 Cholesterol efflux transporter
 Cholesterol efflux transporter abcg5 1.063 0.601
 Cholesterol transporter npc1l1 0.955 0.776
 Nuclear receptor - regular of lipid and sterol metabolism lxr 0.837 0.156
 Nuclear receptor - regular of lipid and sterol metabolism srebp1 0.944 0.851
 Nuclear receptor - regular of lipid and sterol metabolism srebp2 1.174 0.405
ROS metabolism / antioxidant
 Superoxide dismutation sod3 0.739 0.374
Nuclear receptor – control of gene transcription
 Transcription factor rxr 0.789 0.104
Mannose metabolism
 Glycosylation pmm 0.759 0.029

aValues are mean fold change observed in the choline diet fed group in comparison with those in the control group

bP-values in bold indicate significant differences between the two treatments; italicized values represent trends