Fig. 1.

The characteristics of bisulfite converted telomeric WGSBS data. a The distribution of read with distinct number of telomeric blocks in two sample (ENCLB443JJF and ENCLB890RFU). The G-strand and C-strand original reads are color blue and orange respectively. FASTQ1 and FASTQ2 indicate the file containing forward and reversed reads in paired-end NGS sequencing; b A scatter plot showing the numbers of telomeric reads and total reads of 12 WGSBS experiments (red and orange dots represent tissue samples); c UCRs calculated by using forward (+) and reversed (-) reads in three cytosines sites in two samples (ENCLB098BGY, ENCLB167QQW); d The UCRs of technical repeats of two tissues (skeletal muscle myoblast and mouse liver) and two cell lines (HepG2 and H1-hESC); e The box-plot showing the distribution of UCR of three cytosines sites across eleven samples.