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. 2020 Jan 31;21:37. doi: 10.1186/s12882-019-1679-1

Table 3.

Odds ratios from multinomial logistic regression models for CKD stage 3 and stages 4–5 per μm increase in thickness of the full retina, inner retina and outer retina

ETDRS segment Right eye Left eye
CKD stage 3 (vs. stage 1–2) CKD stage 4–5 (vs. stage 1–2) CKD stage 3 (vs. stage 1–2) CKD stage 4–5 (vs. stage 1–2)
OR 95% CI p OR 95% CI p OR 95% CI p OR 95% CI p
Full retinal thickness
 N1 1.00 (0.97, 1.02) 0.89 0.97 (0.94, 0.99) 0.02* 1.00 (0.98, 1.01) 0.70 0.98 (0.95, 1.00) 0.03*
 S1 1.00 (0.98, 1.03) 0.76 0.97 (0.94, 0.99) 0.01* 1.00 (0.98, 1.01) 0.69 0.97 (0.95, 0.99) 0.01*
 T1 1.00 (0.98, 1.02) 0.80 0.99 (0.97, 1.01) 0.33 1.00 (0.98, 1.02) 0.83 0.98 (0.96, 1.00) 0.08
 I1 1.00 (0.97, 1.02) 0.87 0.97 (0.95, 1.00) 0.02* 1.00 (0.98, 1.01) 0.73 0.97 (0.94, 0.99) 0.01*
Inner Retinal Layer
 N1 1.00 (0.97, 1.02) 0.70 0.97 (0.94, 0.99) 0.01* 0.99 (0.97, 1.01) 0.32 0.98 (0.95, 1.00) 0.03*
 S1 1.00 (0.98, 1.03) 0.87 0.97 (0.94, 0.99) 0.01* 0.99 (0.98, 1.01) 0.47 0.97 (0.95, 0.99) 0.01*
 T1 1.00 (0.98, 1.02) 0.92 0.99 (0.96, 1.01) 0.34 1.00 (0.98, 1.01) 0.71 0.98 (0.96, 1.00) 0.09
 I1 1.00 (0.97, 1.02) 0.80 0.97 (0.94, 0.99) 0.02* 0.99 (0.97, 1.01) 0.47 0.97 (0.94, 0.99) 0.01*
Outer Retinal Layer
 N1 1.08 (0.96, 1.22) 0.22 1.01 (0.86, 1.18) 0.93 1.12 (0.99, 1.28) 0.08 1.00 (0.85, 1.17) 0.96
 S1 1.07 (0.93, 1.22) 0.34 1.00 (0.84, 1.18) 0.96 1.08 (0.96, 1.21) 0.20 0.97 (0.83, 1.13) 0.68
 T1 1.10 (0.96, 1.25) 0.19 1.01 (0.84, 1.20) 0.94 1.08 (0.93, 1.26) 0.31 0.99 (0.82, 1.18) 0.90
 I1 1.05 (0.92, 1.21) 0.46 1.05 (0.89, 1.25) 0.54 1.09 (0.96, 1.23) 0.18 1.02 (0.88, 1.18) 0.82

ETDRS Early Treatment Diabetic Retinopathy Study, OR Odds ratio, SD Standard deviation, CI Confidence interval, F Fovea, S1 Superior segment 1, N1 Nasal segment 1, I1 Inferior segment 1, T1 Temporal segment 1.*significant values. Adjustment for age, mean arterial blood pressure, diabetes status, low-density lipoprotein, body mass index, and sex