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. 2020 Jan 31;21:37. doi: 10.1186/s12882-019-1679-1

Table 5.

Odds ratios from multinomial logistic regression models for CKD stage 3 and stages 4–5 per μm increase in thickness of retinal layers supplied by the choroidal vasculature

ETDRS segment Right eye Left eye
CKD stage 3 (vs. stage 1–2) CKD stage 4–5 (vs. stage 1–2) CKD stage 3 (vs. stage 1–2) CKD stage 4–5 (vs. stage 1–2)
OR 95% CI p OR 95% CI p OR 95% CI p OR 95% CI p
Outer plexiform layer
 N1 1.03 (0.97, 1.10) 0.33 1.03 (0.96, 1.11) 0.45 1.00 (0.94, 1.07) 0.89 1.00 (0.93, 1.08) 0.94
 S1 1.02 (0.96, 1.09) 0.46 0.95 (0.86, 1.04) 0.26 1.00 (0.95, 1.06) 0.93 0.93 (0.87, 0.99) 0.03*
 T1 1.07 (0.96, 1.20) 0.22 0.93 (0.81, 1.08) 0.34 1.11 (1.02, 1.22) 0.02* 1.01 (0.90, 1.13) 0.84
 I1 1.01 (0.94, 1.08) 0.78 1.05 (0.98, 1.14) 0.18 1.04 (0.97, 1.12) 0.24 1.08 (1.01, 1.16) 0.03*
Outer nuclear layer
 N1 0.98 (0.94, 1.01) 0.22 0.95 (0.91, 1.00) 0.05* 0.99 (0.96, 1.02) 0.35 0.97 (0.93, 1.01) 0.10
 S1 0.99 (0.95, 1.03) 0.52 0.97 (0.92, 1.02) 0.23 0.99 (0.97, 1.02) 0.45 0.99 (0.96, 1.03) 0.61
 T1 1.00 (0.96, 1.04) 0.89 1.00 (0.97, 1.04) 0.78 0.98 (0.94, 1.01) 0.20 0.98 (0.95, 1.02) 0.42
 I1 0.99 (0.95, 1.03) 0.68 0.96 (0.91, 1.01) 0.10 0.96 (0.92, 1.00) 0.07 0.94 (0.89, 0.98) 0.01*
Retinal pigmented epithelium
 N1 1.02 (0.80, 1.30) 0.88 1.00 (0.75, 1.35) 0.98 1.21 (0.96, 1.53) 0.11 1.01 (0.76, 1.35) 0.93
 S1 1.09 (0.84, 1.42) 0.51 0.97 (0.70, 1.35) 0.87 1.13 (0.91, 1.39) 0.26 0.77 (0.55, 1.07) 0.11
 T1 1.04 (0.80, 1.35) 0.79 1.05 (0.76, 1.44) 0.78 1.09 (0.84, 1.41) 0.53 1.01 (0.74, 1.38) 0.96
 I1 0.94 (0.74, 1.20) 0.63 1.00 (0.75, 1.34) 0.99 1.09 (0.91, 1.31) 0.34 0.99 (0.77, 1.29) 0.96

ETDRS Early Treatment Diabetic Retinopathy Study, OR Odds ratio, SD Standard deviation, CI Confidence interval, F Fovea, S1 Superior segment 1, N1 Nasal segment 1, I1 Inferior segment 1, T1 Temporal segment 1.*significant values. Adjustment for age, mean arterial blood pressure, diabetes status, low-density lipoprotein, body mass index, and sex