Table 2.
Description of the core-genes involved in the PDAC biological process
| Gene symbol | Gene name | Gene symbol | Gene name |
|---|---|---|---|
| Upregulated | |||
| AHNAK2 | AHNAK nucleoprotein 2 | KRT19 | keratin 19 |
| ANLN | anillin actin binding protein | LAMA3 | laminin subunit alpha 3 |
| ANO1 | anoctamin 1 | LAMB3 | laminin subunit beta 3 |
| ASPM | abnormal spindle microtubule assembly | LAMC2 | laminin subunit gamma 2 |
| CAPG | capping actin protein, gelsolin like | LCN2 | lipocalin 2 |
| CEACAM5 | carcinoembryonic antigen related cell adhesion molecule 5 | MET | MET proto-oncogene, receptor tyrosine kinase |
| CEACAM6 | carcinoembryonic antigen related cell adhesion molecule 6 | NQO1 | NAD(P)H quinone dehydrogenase 1 |
| COL10A1 | collagen type X alpha 1 chain | OAS1 | 2′-5′-oligoadenylate synthetase 1 |
| CXCL5 | C-X-C motif chemokine ligand 5 | S100A14 | S100 calcium binding protein A14 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | S100P | S100 calcium binding protein P |
| FXYD3 | FXYD domain containing ion transport regulator 3 | SERPINB5 | serpin family B member 5 |
| GABRP | gamma-aminobutyric acid type A receptor pi subunit | SLC2A1 | solute carrier family 2 member 1 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | SLC44A4 | solute carrier family 44 member 4 |
| GJB2 | gap junction protein beta 2 | SLC6A14 | solute carrier family 6 member 14 |
| GPRC5A | G protein-coupled receptor class C group 5 member A | SLPI | secretory leukocyte peptidase inhibitor |
| GPX2 | glutathione peroxidase 2 | TCN1 | transcobalamin 1 |
| IFI27 | interferon alpha inducible protein 27 | TFF1 | trefoil factor 1 |
| ITGA2 | integrin subunit alpha 2 | TMC5 | transmembrane channel like 5 |
| ITGA3 | integrin subunit alpha 3 | TMPRSS4 | transmembrane protease, serine 4 |
| TSPAN1 | tetraspanin 1 | ||
| Downregulated | |||
| AOX1 | aldehyde oxidase 1 | ||