Table 3.
Luminal subtype reclassification comparing subtypes defined with tumor grade to subtypes defined with Ki67 at various cut points in 2,025 incident invasive luminal breast tumors, Nurses’ Health Study, 1976–2006
Reclassified, n (%) | ||||
---|---|---|---|---|
Ki67 Cut Point | No | Yes | Luminal A to B | Luminal B to A |
6.7% (median) | 1322 (65.3) | 703 (34.7) | 523 (25.8) | 180 (8.9) |
10% | 1434 (70.8) | 591 (29.2) | 364 (18.0) | 227 (11.2) |
14% | 1529 (75.5) | 496 (24.5) | 233 (11.5) | 263 (13.0) |
20% | 1600 (79.0) | 425 (21.0) | 128 (6.3) | 297 (14.7) |
25% | 1636 (80.8) | 389 (19.2) | 76 (3.8) | 313 (15.5) |
30% | 1645 (81.2) | 380 (18.8) | 51 (2.5) | 329 (16.3) |
Percentages may not add to 100 due to rounding