Table 4.
Univariate Analyses on Local Control (Log Rank Test)
| Parameter | p-value |
|---|---|
| Age > or ≤ 56 years | 0.145 |
| Gender | 0.642 |
| Repeated maximal safe resection before ReRT | 0.258 |
| Histopathology WHO grade 3 versus 4 | 0.63 |
| Chemotherapy after ReRT | 0.974 |
| KPS > or ≤ 70 | 0.212 |
| CTV > or ≤ 30 ccm | 0.776 |
| CTV > or ≤ 50 ccm | 0.314 |
| Ki67 ≥ or < 10% | 0.197 |
| Ki67 ≥ or < 20% | 0.014* |
| IDH mutation initially | 0.044* |
| TP53 mutation initially | 0.452 |
| EGFR mutation initially | 0.117 |
| MGMT mutation initially | 0.846 |
| ATRX loss initially | 0.260 |
Note: *p < 0.05.
Abbreviations: ATRX, alpha-thalassemia/mental retardation syndrome X-linked expression; CTV, clinical target volume; EGFR, epidermal growth factor receptor; IDH, Isocitrat dehydrogenase; KPS, Karnofsky Performance Score; MGMT, O-6-methylguanine-DNA methyltransferase; ReRT, reirradiation; TP53, Tumor protein 53; WHO, World Health Organization.