Figure 8.

FG-4592 pretreatment restrains fibrosis progression on the 14th day after FA injection. (a) Deposition of fibrils (blue) and infiltration of inflammatory cells around vessels are indicated with Masson's trichrome staining. Bar, 50 μm. Immunostaining of fibronectin and collagen IV is shown in brown. (b) Western blotting of fibronectin. (c) Western blotting of collagen IV. (d) Western blotting of vimentin. (e) Semiquantitative measurement of fibronectin. (f) Semiquantitative measurement of collagen IV. (g) Semiquantitative measurement of vimentin. The values are expressed as the means ± SEM. ^∗P < 0.05 versus the control group. ^#P < 0.05 versus the FG-4592 group. ^&P < 0.05 versus the FA group.