Table 1.
Frequency of IDH1 Mutations in WHO II astrocytoma Patients.
| Country | Total | IDH1 | IDH1 |
|---|---|---|---|
| Mutated | Mutated rate | ||
| China (present study) | 115 | 79 | 68.70% |
| China 12 | 50 | 29 | 58.00% |
| China 13 | 206 | 145 | 70.39% |
| China 14 | 125 | 86 | 68.80% |
| China 15 | 37 | 25 | 67.57% |
| China 16 | 417 | 309 | 74.10% |
| China 17 | 111 | 72 | 64.86% |
| Italy 18 | 87 | 66 | 75.86% |
| France 19 | 47 | 40 | 85.11% |
| Germany 20 | 71 | 54 | 76.06% |
| Germany 21 | 431 | 332 | 77.03% |
| America 22 | 233 | 203 | 87.12% |
| America 23 | 81 | 70 | 86.42% |
| America 24 | 75 | 64 | 85.33% |
| America 25 | 159 | 141 | 88.68% |
| CGGA 26 | 117 | 82 | 70.01% |
| TCGA | 415 | 323 | 77.83% |
Compared with Caucasians, Asians have a relatively low frequency of IDH mutations rate; CGGA=Chinese Glioma Genome Altas; TCGA=The Cancer Genome Atlas