Table 3.

Univariate and multivariate analyses of different prognostic variables in infiltrating glioma patients

Parameters	Univariate analysis		Multivariate analysis (COX)
	Median OS	p	RR	95.0% CI for Exp(B)		P
	(month)	(Log rank)		Lower	Upper
Gender		0.278	1.176	0.826	1.674	0.368
Male	24
Female	27
Age		<0.001*	0.962	0.668	1.385	0.835
≤ 45 years old	33
> 45 years old	18
WHO Grade		<0.001*	1.311	0.734	2.343	0.360
Low (II)	62
High (III, IV)	18
IDH1		<0.001*	0.262	0.162	0.425	<0.001*
Mutated	67
Wildtype	17
ATRX		0.457	0.963	0.67	1.384	0.839
Mutated	28
Wildtype	25
P53		0.043*	1.18	0.808	1.724	0.392
Mutated	23
Wildtype	29
PHH3		<0.001*	1.129	0.734	1.738	0.581
<5	45
≥5	16
Ki67		<0.001*	1.064	0.642	1.765	0.809
<10%	59
≥10%	19
1p/19q		<0.001*	0.394	0.236	0.581	<0.001*
Codeletion	84
Intact	25
TERTp		<0.001*	1.727	1.172	2.544	0.006*
Mutated	22
Wildtype	33
MGMTp		0.004	0.57	0.397	0.819	0.002*
Methylated	35
Unmethylated	23