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Expression of mutant genes in cell lines
| Gene | Expression of Cell Line |
|---|---|
| KRAS | Occurred in almost all of the primary tumors of pancreatic cancer, but the BxPC-3 cell line is WT |
| SMD4/DPC4 | Capan-2, MIA PaCa-2, PANC-1, SU.86.86 without SMD4 gene inactivation |
| TP53 | Its mutation occurs in 50% of pancreatic malignant tumors and is associated with late tumor progression |
| CDKN2A/P16 | Basically all pancreatic cancer cell lines have inactivation of the P16 gene |
