Appendix Table 1.
Overview of Interventions
| Weeks 1–8 | Hypnotherapy | Pharmacotherapy |
|---|---|---|
| Week #1 | Give study overview, explain bladder physiology, UUI pathophysiology, hypnotherapy principles. Participants discuss any fears/concerns regarding interventions. Patients set goals for this session. Perform hypnosis; induction & progressive relaxation/deepening/ therapeutic suggestions/terminate hypnosis. Debrief. | Give study overview, explain bladder physiology, UUI pathophysiology, discuss medications & mechanism of action. Participants discuss any fears/concerns regarding interventions. Medication instructions given and medication dispensed. |
| Week #2 | Review change/persistence in UUI symptoms & prior week’s experiences, address UUI associated emotions/life impact, introduce self-hypnosis.Proceed with hypnosis/debrief (See Week #1). | Review change/persistence in UUI symptoms & prior week’s experiences, tolerability of meds discussed. Coping mechanisms re: side effects discussed. If needed, arrangements made for medication change. |
| Week #3 | Identify emotional triggers or responses associated based on self-discovery of emotional/physical connection with UUI & develop positive actions to deal with these emotions. Proceed with hypnosis/debrief (See Week #1). | Review change/persistence in UUI symptoms& prior week’s experiences, discuss tolerability of medications. Coping mechanisms re: side effects discussed. If needed, arrangements made for medication change. |
| Week #4 | Assist participant develop therapeutic suggestions & imagery to cope with UUI. Proceed with hypnosis/debrief (See Week #1). | Same as above.Medication instructions given and medication dispensed. |
| Week #5 | Provide digital recording for participant; specifically prepared for patient & for hypnotherapy home practice (based on work from week #4, emphasizes ego strengthening). Patients develop own therapeutic suggestions to reverse UUI after identifying beliefs that limit their bladder health. Proceed with hypnosis/debrief (See Week #1). | Same as Week #3. |
| Week #6 | Have participant reflect on their past (including responses resulting in current UUI associated behavior; consider how to alter this behavior). Proceed with hypnosis/debrief (See Week #1). | Discuss urgency incontinence triggers & participant encouraged to develop coping mechanisms. Same as above. |
| Week #7 | Focus on integration of resources developed through hypnotherapy to improve UUI & overall health, countering negative emotions/responses related to emotional & physical connections.Proceed with hypnosis/debrief (See Week #1). | Same as above. |
| Week #8 | Focus on healing imagery & continuation of self-hypnosis. Proceed with hypnosis/debrief (See Week #1). | Same as above. Interventionist discusses potential setbacks & emphasizes these are temporary. Medication side effects & copingmechanisms reviewed. Medications dispensed. |