Vertex-wise group differences between individuals with MCI and cognitively healthy older adults after performing PVC and adjusting for sex. Comparisons of (A) CBF, (B) ALFF, and (C) cortical thickness between groups. Significantly reduced CBF was found regionally in the right temporal/parietal cortex as well as lateral and medial frontal cortex (cluster corrected q <0.05), while no significant difference was found in either ALFF or cortical thickness after cluster-wise correction.
Abbreviations: MCI, mild cognitive impairment; CBF, cerebral blood flow; ALFF, amplitude of low frequency fluctuations; PVC, partial volume correction; FDR, False discovery rate.