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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Neurobiol Aging. 2019 Nov 6;86:64–74. doi: 10.1016/j.neurobiolaging.2019.10.023

Figure 2.

Figure 2.

Vertex-wise local correlations between CBF, ALFF, the volume of WML, and cortical thickness in individuals with MCI and cognitively healthy older adults after performing PVC and adjusting for sex. (A) A significant negative correlation between CBF and the volume of WML was noted in MCI (FDR corrected q <0.05), while not in cognitively healthy older adults. (B) A significant negative correlation between ALFF and the volume of WML was noted in cognitively healthy older adults (FDR corrected q < 0.05), but not in MCI. (C) A significant positive correlation between ALFF and cortical thickness was noted in both groups (FDR corrected q < 0.05). Color bar indicates scale of Pearson’s correlation coefficient.

Abbreviations: MCI, mild cognitive impairment; CBF, cerebral blood flow; WML, white matter signal lesions; CTh, cortical thickness; PVC, partial volume correction.