Table 3.
Levels of serum DPP-IV activity, sCD26 concentration, and anti-CD26/DPP-IV autoantibody isotypes according to the colonoscopy result in FIT-positive individuals.
| Colonoscopy finding | DPP4 Mean ± SD (mU/mL) |
sCD26 Mean ± SD (ng/mL) |
IgA Mean ± SD (Abs450nm) |
IgG Mean ± SD (Abs450nm) |
IgM Mean ± SD (Abs450nm) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | p value1 | N | p value1 | N | p value1 | N | p value1 | N | p value1 | ||||||
| NCF | 7 | 33.19 ± 18.40 | 8 | 433.96 ± 203.46 | 8 | 0.24 ± 0.11 | 8 | 0.25 ± 0.07 | 8 | 0.11 ± 0.08 | |||||
| BP | 12 | 39.90 ± 21.62 | 12 | 465.20 ± 116.50 | 11 | 0.20 ± 0.12 | 11 | 0.25 ± 0.06 | 11 | 0.17 ± 0.08 | |||||
| HP | 6 | 36.78 ± 19.57 | 0.924 | 6 | 497.18 ± 193.87 | 0.903 | 6 | 0.21 ± 0.09 | 0.899 | 6 | 0.23 ± 0.10 | 0.408 | 6 | 0.12 ± 0.06 | 0.484 |
| AD | 20 | 48.64 ± 26.63 | 0.227 | 20 | 440.76 ± 79.77 | 0.808 | 19 | 0.25 ± 0.11 | 0.365 | 19 | 0.28 ± 0.07 | 0.184 | 19 | 0.18 ± 0.09 | 0.439 |
| CRC | 1 | 40.52 | 1 | 605.93 | 1 | 0.21 | 1 | 0.34 | 1 | 0.003 | |||||
| NCF+BP+HP | 25 | 37.27 ± 19.67 | 26 | 462.97 ± 160.10 | 25 | 0.22 ± 0.11 | 25 | 0.25 ± 0.07 | 25 | 0.14 ± 0.08 | |||||
| AD+CRC | 21 | 48.25 ± 26.01 | 0.2212 | 21 | 448.62 ± 85.70 | 0.8982 | 20 | 0.25 ± 0.11 | 0.3092 | 20 | 0.28 ± 0.07 | 0.0832 | 20 | 0.17 ± 0.1 | 0.3852 |
NCF: no colorectal finding; BP: benign pathology; HP: hyperplastic polyp; AD: adenomas; CRC: colorectal cancer; 1Mann-Whitney U test for comparison of NCF+BP vs. the other groups; 2Mann-Whitney U test for comparison of NCF+BP+HP vs. AD+CRC.