Table 1.

Main effects of NAGlys and NASers mediated by different GPCRs and other receptors.

	Glycine	Serine
N-arachidonoyl	Calcium mobilization [31] Cancer cell proliferation [58] Cell apoptosis and migration [34,35] Cell morphology [40] Inflammation [36] Intraocular pressure [38] Microglial-neuronal communication [39] Neuropathic pain [45] Thermal analgesia [46]	Angiogenesis [59] Anti-microbial effect [60] Cell proliferation [61] Cytoskeleton reorganization [62] Neuroprotection [61,63,64]
N-Oleoyl	Body and motor activities [54] Cancer cell proliferation [58] Energy homeostasis [52] Food intake [55] Nicotine addiction [56]	Bone metabolism [65,66]
N-Palmitoyl	Calcium mobilization [67] Primary dysmenorrhea [68]	Neuroprotection [64]