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. 2019 Dec 11;9(12):855. doi: 10.3390/biom9120855

Table 1.

Evaluation of EGCG and EGCGox’s effects on the insulin aggregation process.

Assessed by Change in t50
Protein Conditions EGCG EGCG ox
Insulin PB-Q Inhibitory 1 Inhibitory
PB-A No Effect Inhibitory
AC-Q No Effect Inhibitory
AC-A No Effect Inhibitory
α-synuclein pH 7 Inhibitory Inhibitory
pH 6 No Effect Inhibitory
Assessed by Change in Imax
Protein Conditions EGCG EGCG ox
Insulin PB-Q Inhibitory Inhibitory
PB-A No Effect Inhibitory
AC-Q No Effect Enhancing
AC-A No Effect Enhancing
α-synuclein pH 7 Inhibitory Inhibitory
pH 6 Inhibitory Inhibitory

1 Established by comparing experimental values of t50 or Imax of control samples with the ones determined in the presence of EGCG or EGCGox using one-way ANOVA (See Figure S7). p < 0.01 was accepted as statistically significant.