Ergur 2009.
Methods | Study design: prospective, randomised clinical trial of intravitreal bevacizumab for PDR Unit of randomisation: participant Unit of analyses: eye Follow‐up: 1 day, 1 week, 1 and 6 months |
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Participants | Country: Turkey Setting: M.D., Ministry of Health Atatürk Research and Training Hospital 2st Eye Clinic Ankara, Turkey Number of participants: 16 (19 eyes) Exclusions post‐randomisation: 0 Losses to follow‐up: 0 Age (mean (SD)): 71.4 (4.6) years in bevacizumab plus PRP group, 68.3 (3.4) years in PRP group Gender: 9 men and 7 women Inclusion criteria: people with PDR Exclusion criteria: people with history of cataract surgery or thromboembolic ictus |
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Interventions | Treatment: intravitreal bevacizumab 1.25 mg/0.05 mL, 20 days before PRP, 3 sessions Control: PRP/week/3 weeks, 3 sessions |
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Outcomes | Primary: BCVA, intraocular pressure, biomicroscopic examination, fundus examination, colour fundus photography, fluorescein leakage areas | |
Notes | Funding: not reported Trial registration: not reported Date conducted: not reported Conflict of interest: none reported |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: not described |
Allocation concealment (selection bias) | Unclear risk | Comment: not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Comment: not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: not described |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: there were 0 losses |
Selective reporting (reporting bias) | Low risk | Comment: the results of the variables were described in the methods section |