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. 2014 Nov 24;2014(11):CD008721. doi: 10.1002/14651858.CD008721.pub2

Ergur 2009.

Methods Study design: prospective, randomised clinical trial of intravitreal bevacizumab for PDR
Unit of randomisation: participant
Unit of analyses: eye
Follow‐up: 1 day, 1 week, 1 and 6 months
Participants Country: Turkey
Setting: M.D., Ministry of Health Atatürk Research and Training Hospital 2st Eye Clinic Ankara, Turkey
Number of participants: 16 (19 eyes)
Exclusions post‐randomisation: 0
Losses to follow‐up: 0
Age (mean (SD)): 71.4 (4.6) years in bevacizumab plus PRP group, 68.3 (3.4) years in PRP group
Gender: 9 men and 7 women
Inclusion criteria: people with PDR
Exclusion criteria: people with history of cataract surgery or thromboembolic ictus
Interventions Treatment: intravitreal bevacizumab 1.25 mg/0.05 mL, 20 days before PRP, 3 sessions
Control: PRP/week/3 weeks, 3 sessions
Outcomes Primary: BCVA, intraocular pressure, biomicroscopic examination, fundus examination, colour fundus photography, fluorescein leakage areas
Notes Funding: not reported
Trial registration: not reported
Date conducted: not reported
Conflict of interest: none reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: not described
Allocation concealment (selection bias) Unclear risk Comment: not described
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Comment: not described
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comment: not described
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: there were 0 losses
Selective reporting (reporting bias) Low risk Comment: the results of the variables were described in the methods section