Figure 10.
From Principal Component Analysis, projections of the trajectories onto planes by the first three eigenvectors. (A) Projection of trajectories into PC1, PC2, and PC3 for the CTD-CTD interface, (D) Projection of trajectories into PC1, PC2, and PC3 for the Dimer interface and (G) Projection of trajectories into PC1, PC2, and PC3 for the Oligomeric interface. The color scale from blue to white to red shows that there are periodic jumps between these conformers through the trajectory. (B) Visualization of the molecular motions along (B) PC1 and (C) PC2 for CTD-CTD, (E) PC1 and (F) PC2 for the Dimer, and (H) PC1 and (I) PC2 for the Oligomeric interfaces. The gray shading shows regions with large motion.