. Author manuscript; available in PMC: 2020 Oct 31.

Published in final edited form as: J Phys Chem B. 2019 Oct 16;123(43):9045–9053. doi: 10.1021/acs.jpcb.9b04674

Table 2.

For each of the inter-domain communities pictured in Figs. 7(D-F) for each interface structure, a list of amino acids in each inter-domain network community that are dynamically connected to amino acids on the other domain. The bottom row of the table provides the sum of all inter-domain amino acid connections for each interface.

Community	Oligomer		Dimer		CTD-CTD
Community	NTD-1	NTD-2	NTD-1	NTD-2	CTD-1	CTD-2
Comm-1	P93	P187	I54, A55, D56, D57	R52	V306, I307, T308	T304
	K90, I92	A189	A55, I59	L117
	M89, K90	T190	A55, M116	M116
	L88, M89	W191	T112	L117
	L88, V87	T192	R52, M116, L117	A55
	Q91	A188, A189	R52	D57
	I92	A189	L117	I59
			D109, S110, A113	D109
			A113, L117	T112
Comm-2	V100	E160, F161, V162, L163			P234	Q238, T242
	L186, P187	P93
	S70, V100	P164
	A72, Q184	W95
Comm-3	T190	M89, K90			L295	R214, S316
Comm-3	W191	L88, M89			P297	K212, L213, P215
Comm-4	W95, Q160, F161, L163	V100			H315	I293
	P165	S70
	W95	L186
Comm-5	D102	P165
Total Connections	33		19		11