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CD4+ cells in the central nervous system (CNS). The number of CD4+ cells in the CNS of sham-treated mice was significantly greater than that in naïve mice [both n=6, 3,139±691 vs. 997±469, mean±standard error of the mean (SEM); p<0.05 by the Mann-Whitney U test]. However, the number of CD4+ cells in the CNS of Goreisan-treated mice (n=5, 2,649±579) was not significantly different from that in the CNS of naïve mice.
