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Isoproterenol administration test (A) and mexiletine administration test (B). Continuous infusion of isoproterenol does not induce paradoxical QT prolongation (A). Mexiletine 2.5 mg/kg administration shortens the QT interval by 40 ms and does not change the saddleback-type ST elevation, even in the second and third intercostal spaces (B). ISP: isoproterenol, γ: μg/kg/min
