Table 1:

Sterility of lipodystrophic and ob mice is rescued by mouse embryonic fibroblast injection. The denominator in the resulting pregnancies represents the number of genetically modified mice (i.e. LD or ob) as all crosses were performed with one male and two females in a cage.

Male	Female	Resulting pregnancies
LD	WT	0/6
LD+leptin	WT	5/6
WT	LD	0/6
WT	LD+leptin1,2	6/6
WT	LD+leptin2,3	6/6
WT	LD+MEFs	8/8
WT	Ob	0/6
WT	Ob+MEFs4	6/6

¹Leptin was injected until delivery

²Pups died within 48 hours of delivery

³Leptin was administered until E14 from timed matings

⁴Pups survived until adulthood.