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Histiocytic sarcoma of the base of tongue in a 49 year old man, treated with radical radiotherapy 60 Gy in 30 fractions. Prior to treatment a T1-weighted MRI with gadolinium enhancement demonstrated base of tongue mass in A) axial and B) sagittal views, and a FDG-PET-CT showed highly avid base of tongue (SUVmax 16) mass in C). FDG-PET-CT 4 months following completion of radiotherapy showed a complete metabolic response in D).
