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. 2019 Sep 23;10(1):43–80. doi: 10.1016/j.jceh.2019.09.007
Consensus statements Level Grade
  • AFP is the only tumor marker that has undergone extensive evaluation.

I
  • AFP alone is not recommended either in surveillance or diagnosis of HCC.

II-2 Strong
  • High levels of tumor markers are associated with worse prognosis in HCC patients.

I
  • AFP may have a role in assessing response to loco-regional therapy and tumor recurrence hence recommended to be done prior to loco-regional therapy.

II-2 Strong
  • Molecular classification of HCC is not ready for clinical application.

II-2 Weak