Table 1.
Descriptive characteristics of study participants
| Enrolled in study and analysed in ITT (n=25) | Started maintenance phase (n=21) | |
| Sex | ||
| Male, n (%) | 8 (32) | 6 (29) |
| Female, n (%) | 17 (68) | 15 (71) |
| Age (years) at inclusion, mean (SD) | 53.2 (8.4) | 52.5 (8.6) |
| Age (years) at TRD onset, mean (SD) | ||
| Self-report | 28.5 (15.2) | 28.0 (15.0) |
| Diagnosis | 37.8 (9.8) | 37.3 (9.9) |
| Years since TRD onset (diagnosis), mean (SD) | 15.3 (9.1) | 15.1 (8.5) |
| Estimated IQ, mean (SD) | 95.3 (15.0) | 95.6 (14.9) |
| Number of past medications, mean (SD) | 10.8 (3.3) | 10.9 (3.2) |
| Number of past ECT series, mean (SD) | 2.3 (1.7) | 2.2 (1.4) |
| Number of past ECT sessions, mean (SD) | 68.9 (103.6) | 70.7 (112.1) |
| Patients with past suicide attempts, n (%) | 7 (28) | 6 (29) |
| TRD episodes, n (%) | ||
| 1 | 10 (40) | 10 (48) |
| 2 | 3 (12) | 3 (14) |
| >2 | 12 (48) | 8 (38) |
| Duration of current episode, months (SD) | 83.8 (76.2) | 89.0 (81.1) |
| Hospital | ||
| Academic Medical Center | 12 | 11 |
| St Elisabeth Hospital | 13 | 10 |
| Duration of follow-up (weeks), range (mean, SD) | 20.9–154.0 (99.4, 39.2) | 56∙6–154.0 (112.0, 28.1) |
| Duration of maintenance phase (weeks), range (mean, SD) | – | 14.0–91.4 (62.4, 15.6)* |
| Number of outpatient clinic visits during maintenance phase, range (median) | – | 2–49 (7)* |
*In these descriptive analyses, two patients were excluded with measurements at T2 but no further follow-up during the maintenance phase due to withdrawal from study (lack of effect).
ECT, electroconvulsive therapy; ITT, intention-to-treat; T2, start of the maintenance phase; TRD, treatment-resistant depression.