Table 2.

Bacterial taxa associated with host infection status, at phylum and genus level, identified using the interpolated area under the receiver operating characteristic (ROC) curve (= AUC) in a random forest (RF) classifier. The predicted mean decreasing accuracy (MDA) score generated for each taxon, using the estimated RF model, is also shown. AUCs > 0.5 are not shown. In comparative analyses between gut microbial profiles of helminth-infected and -uninfected hosts, only phyla and genera making up > 1% and > 0.5% of the overall microbiota, respectively, in at least one group are reported

		Relative abundance (%)
Phylum	Genus	AUC	Fold change	Uninfected	Infected
Non-rodents
Actinobacteria	Collinsella	0.56	− 0.64	2.37	3.69
Actinobacteria	Bifidobacterium	0.54	0.85	2.68	2.26
Bacteroidetes		0.58	1.18	18.83	16.01
	Bacteroides	0.60	0.55	6.97	3.83
	Parabacteroides	0.58	0.71	0.51	0.37
	Alloprevotella	0.51	0.69	1.05	0.72
Firmicutes		0.56	− 1.10	48.94	54.05
	Streptococcus	0.52	0.65	2.58	1.69
	Catenibacterium	0.53	− 0.41	0.33	0.80
	Holdemanella	0.57	− 0.51	0.76	1.48
	Lachnoclostridium	0.52	0.98	0.58	0.57
	Subdoligranulum	0.55	0.83	2.39	1.99
	Veillonella	0.54	− 0.46	0.29	0.62
	Peptoclostridium	0.55	− 0.48	0.84	1.76
	Blautia	0.54	− 0.81	1.77	2.19
	Megamonas	0.54	− 0.45	0.35	0.78
	Romboutsia	0.52	− 0.72	0.65	0.89
	Faecalibacterium	0.55	0.88	2.64	2.32
	Dialister	0.54	0.78	0.97	0.76
	Turicibacter	0.52	− 0.29	0.16	0.56
Fusobacteria		0.55	− 1.21	1.70	2.06
	Fusobacterium	0.57	− 0.91	1.60	1.77
Rodents
Actinobacteria		0.54	1.33	1.27	0.95
	Bifidobacterium	0.62	1.66	0.63	0.38
Bacteroidetes		0.68	1.51	46.02	30.4
	Alistipes	0.57	− 1.08	1.66	1.79
	Bacteroides	0.61	− 1.06	1.06	1.13
	Odoribacter	0.57	− 1.5	0.53	0.8
Firmicutes		0.65	− 1.25	48.33	60.46
	Turicibacter	0.58	5.44	1.83	0.34
	Lactobacillus	0.69	− 2.2	15.37	33.82
	Faecalibaculum	0.62	1.98	3.01	1.52
	Dubosiella	0.61	2.97	1.24	0.42
	Candidatus Arthromitus	0.62	− 59.75	0.01	0.74
	Roseburia	0.59	1.05	0.63	0.6
Proteobacteria	Desulfovibrio	0.62	1.94	0.64	0.33
	Helicobacter	0.57	− 7.69	0.1	0.74
Verrucomicrobia		0.58	− 3.09	0.7	2.16
	Akkermansia	0.59	− 3.14	0.68	2.14