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A, Images of SA‐β‐gal staining in the tissues of 16‐ to 18‐week‐old mice treated with PBS or DOX at 2 weeks of age (n = 4). mRNA levels of (B) p16, (C) p21, and (D) IL6 in the tissues of PBS and DOX‐treated mice. Results expressed as means ± SEM (n = 4, *P < .05, **P < .01)
