Table 1.
Slope and intercept values obtained from dose–response analysis in MM1.S cells infected with pLKO.1 or ACA11 after treatment with bortezomib or melphalan
| Treatment | Condition | Slope | Intercept | p value | |
|---|---|---|---|---|---|
| Cell number | Bortezomib | pLKO.1 | −0.13 ± 0.01 | 12.29 | 0.008 |
| ACA11 | −0.26 ± 0.01 | 8.29 | |||
| Melphalan | pLKO.1 | −0.02 ± 0.01 | 29.27 | 0.33 | |
| ACA11 | −0.05±0.01 | 29.79 | |||
| Cell proliferation | Bortezomib | pLKO.1 | −0.06 ± 0.02 | 15.10 | 0.06 |
| ACA11 | −0.13 ± 0.01 | 12.05 | |||
| Melphalan | pLKO.1 | −0.01 ± 0.004 | 55.08 | 0.32 | |
| ACA11 | −0.04 ± 0.023 | 33.94 |