Figure 3.

Reduced glutathione (GSH) content in the organs of infected aged mice. Fifteen‐month‐old mice were infected with a mouse‐adapted strain of influenza A/Puerto Rico/8/34 (H1N1; PR8) and treated with Placebo (I + Placebo) or GSH‐C4 (I + GSH‐C4) as described in the Materials and Methods section. At day 8 pi, GSH level was quantified in the spleen, lymph nodes, pancreas, and brain as described in the Materials and Methods section. Values represent the mean ± SD of three mice each performed in duplicate (n = 6). Unpaired data were analyzed with the Student's t test with Welch correction: *P < 0.05, **P = 0.002 vs Ctr (mock‐infected mice); §P < 0.05 vs I + Placebo