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. 2019 Feb 13;1(5):283–295. doi: 10.1096/fba.2018-00044

Figure 2.

Figure 2

Complete prevention of steatosis in the livers of L1‐Tg mice fed a HFD by ezetimibe administration. A, Photographic images of the livers of L1‐Tg mice fed a high‐fat diet (HFD) containing ezetimibe (Eze) for 2 weeks. The coin diameter was 1 cm. B‐E, Hepatic cholesterol levels (B), hepatic triglyceride (TG) levels (C), body weight (BW) (D), and the ratios of liver weight to BW (L/B ratio) (E) in each group of mice. Data are expressed as the mean ± SEM n = 4 (non‐administered groups) and 7 (Eze‐administered groups). Statistical analyses for significant differences were performed using Bartlett's test, followed by a parametric Tukey–Kramer multiple‐comparison test (##P < 0.01 vs control fat diet (CFD) controls; **P < 0.01 vs. the other groups; *P < 0.05 among two groups; NS, not significantly different among groups).