Table 4.
Univariate association between additional oral antibiotic bowel preparation and postoperative complications, risk-adjusted against chronic kidney disease and serum albumin class prior to operation
| Complication | MBP only group (n = 156) | MBP+OABP group (n = 155) | Adjusted NNTa | Adjusted OR (95% CI) | P-value |
| Surgical site infections, n (%): | 25 (16.0) | 7 (4.5) | 8.4 | 0.224 (0.092, 0.546) | 0.001 |
| Superficial | 16 (10.3) | 4 (2.6) | 12.9 | 0.227 (0.073, 0.707) | 0.011 |
| Organ space | 11 (7.1) | 5 (3.2) | 23.6 | 0.382 (0.126, 1.160) | 0.089 |
| Anastomotic leak, n (%) | 3 (1.9) | 2 (1.3) | 149.6 | 0.648 (0.104, 4.041) | 0.642 |
| Clostridium difficile colitis, n (%) | 0 | 0 | – | – | – |
| Ileus, n (%) | 16 (10.3) | 18 (11.6) | (210.0) | 1.052 (0.507, 2.184) | 0.892 |
| Urinary tract infection, n (%) | 11 (7.1) | 6 (3.9) | 26.0 | 0.437 (0.152, 1.258) | 0.125 |
| Chest infection, n (%) | 10 (6.4) | 13 (8.4) | (83.6) | 1.202 (0.501, 2.883) | 0.680 |
| Mortality, n (%) | 3 (1.9) | 1 (0.6) | 72.9 | 0.283 (0.028, 2.894) | 0.287 |
| Postoperative length of hospital stay (days), mean (SD) | 10.2 (10.4) | – | – | Beta –2.46 (–4.375, –0.541) | 0.012 |
a Risk-adjusted number needed to treat (NNT) for benefit (number needed to treat for harm).
CI, confidence interval; MBP, mechanical bowel preparation; OABP, oral antibiotic bowel preparation; OR, odds ratio; SD, standard deviation.