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. 2020 Jan 28;13:853–863. doi: 10.2147/OTT.S231493

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© 2020 Yang et al.

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Overall survival. (A) +, ER persistent positivity; + to -, ER loss in expression; -, ER persistent negativity; - to +, ER gains in expression; (B) +, PR persistent positivity; + to -, PR loss in expression; -, PR persistent negativity; - to +, PR gains in expression; (C) Group1, HR⁺/HER2^−/+ to HR⁺/HER2^−/+; Group 2, HR⁺/HER2^−/+ to HR⁻/HER2^−/+; Group 3, HR⁻/HER2⁻to HR⁻/HER2⁻; Group 4, HR⁻/HER2^−/+ to HR⁺/HER2^−/+.