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. 2020 Jan 28;13:853–863. doi: 10.2147/OTT.S231493

Table 3.

Comparison of Tumor Subtype Between Primary and Recurrent Tumors

HR, HER2 Status in Metastasis Sites Total
HR+/HER2- HR+/HER2+ HR−/HER2+ HR−/HER2- HR−/HER2 Not Sure HR+/HER2 Not Sure
HR, HER2 status in primary sites
 HR+/HER2− 77(28.5) 11(4.1) 2(0.7) 15(5.6) 5(1.9) 21(7.8) 131(48.5)
 HR+/HER2+ 5(1.9) 32(11.9) 10(3.7) 2(2.9) 2(2.9) 10(3.7) 61(22.6)
 HR-/HER2+ 0(0) 5(1.9) 16(6) 5(1.9) 4(1.5) 6(2.2) 36(13.3)
 HR-/HER2− 13(4.8) 3(1.1) 4(1.5) 20(7.4) 2(0.7) 0(0) 42(15.5)
 Total 95(35.2) 51(18.9) 32(11.9) 42(15.6) 13(4.8) 37(13.7) 270

Note: −, Means receptor expression negative; +, Means receptor expression positive.

Abbreviations: HER2, human epidermal growth factor receptor 2; HR, hormone receptor.