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. 2020 Jan 28;14:371–393. doi: 10.2147/DDDT.S236586

Figure 1.

Figure 1

Synthetic route to the amide analogs 1–4, 6, 7, 9–24, 26–66. Reagents and conditions: (A) PCl3, toluene, reflux. (B) CDI, THF, reflux. (C) mw, 160 °C. For R1, R2, and R3 see Table 1.