Skip to main content
. 2020 Jan 28;14:371–393. doi: 10.2147/DDDT.S236586

Table 1.

MAO A and B Inhibition Percentages Measured at One-Point Screening of Anilides (Screening Concentration 1 µm)

n % Inhibition at 1 µm n % Inhibition at 1 µm
MAO A MAO B MAO A MAO B
1 12±8 5±3 15 9±3 7±5
2 11±5 2±4 16 20±12 14±10
3 29±3 27±3 17 10±5 69±28
4 24±20 29±3 18 18±5 24±9
5 1±2 −2±3 19 13±2 11±7
6 16±7 7±5 20 72±2 61±4
7 82±2 46±4 21 13±1 10±7
8 10±4 1±3 22 2±1 14±3
9 14±7 14±5 23 23±3 25±4
10 28±8 25±3 24 27±4 48±5
11 48±3 85±1 25 25±2 11±4
12 28±8 5±3 26 11±2 2±3
13 50±4 32±10 27 20±6 44±23
14 49±5 18±11 28 8±4 5±2
29 15±1 87±5 41 8±4 85±3
30 7±3 38±7 42 5±3 30±5
31 82±1 104±2 43 4±8 0±5
32 45±5 66±5 44 34±3 6±2
33 74±2 96±2 45 13±2 36±4
34 71±5 96±1 46 13±3 68±2
35 8±1 5±10 47 35±3 36±4
36 6±4 84±12 48 5±5 1±2
37 13±4 30±10 49 3±3 13±6
38 9±2 −2±2 50 6±5 62±2
39 20±8 91±1 51 3±4 34±2
40 8±4 6±2 52 19±4 80±4
53 38±6 87±1 60 −12±18 67±2
54 7±9 24±26 61 −3±5 72±2
55 44±4 91±2 62 −2±20 48±5
56 1±2 47±5 63 −3±19 44±23
57 9±9 62±7 64 84±2 80±4
58 11±7 58±1 65 52±10 92±4
59 −4±10 28±2 66 11±8 40±31

Notes: aData represent mean values ± standard deviation of at least two independent experiments each performed in duplicates (global fit). Percentage values were calculated relative to control (set to 100% remained activity). Bold values represent inhibition rates >90 % MAO B and highest MAO A inhibitions.