Table 4. Results of repeated measures ANOVA (Experiment 2).

Adult zebrafish from all treatment groups generally habituated to the novel tank across the duration of the test (6 minutes), but there was no significant interaction between time and drug treatment or stress on any of the behavioral measures of anxiety (N = 16 − 18 in each group). Significance (p < 0.05, indicated with bold text) for all dependent variables were determined with a repeated-measures ANOVA with Greenhouse-Geisser correction.

	Total distance (cm)		Mean ambulatory speed (cm/s)		Time immobile (s)		Number of entries to top		Total time in top (s)		Distance in top (cm)
	F	p	F	p	F	p	F	p	F	p	F	p
Within-subjects Effects
Time	9.795	<0.001	2.022	0.133	15.136	<0.001	7.112	<0.001	15.075	<0.001	13.679	<0.001
Time* Stress	4.262	0.005	2.134	0.118	1.705	0.190	0.766	0.545	0.375	0.822	0.898	0.452
Time* Drug	0.573	0.644	0.240	0.802	0.948	0.381	0.425	0.785	0.215	0.927	0.350	0.811
Time* Stress* Drug	1.811	0.136	3.226	0.039	0.392	0.651	0.771	0.541	0.920	0.451	0.620	0.620
Between-subjects Effects
Stress	0.308	0.581	0.118	0.732	3.050	0.085	5.886	0.018	2.768	0.101	5.100	0.027
Drug	0.191	0.663	0.050	0.824	2.931	0.092	3.131	0.082	4.062	0.048	0.750	0.390
Stress* Drug	0.100	0.753	0.123	0.727	2.018	0.160	1.431	0.236	0.956	0.332	1.876	0.176