Table 1.

Treatment protocol for first and subsequent BRD treatments

BRD treatment sequence	Treatment decision cutoffs	Treatment
No treatment	Visual signs of BRD, rectal temperature <40°C and CALA score <2	No treatment
First treatment-less severe BRD, <60 DOF	Visual signs and CALA score 2, or no visual signs and CALA score 2, or visual signs and rectal temperature ≥40°C, or no visual signs and rectal temperature ≥40°C	Tilmicosin (Micotil, Elanco Animal Healthy, West Ryde, Australia)
First treatment-severe BRD, <60 DOF	CALA score 3 with or without visual signs, or rectal temperature ≥ 40°C and CALA score ≥2 with or without visual signs	Tulathromycin (Draxxin, Zoetis Animal Health, NJ, USA)
Second treatment	Pulled for BRD a second time or received Tulathromycin for the first BRD treatment	Oxytetracycline (Engemycin, MSD Animal Health, Wellington, New Zealand)
Third treatment	Pulled for BRD a third time	Florfenicol (Nuflor, Merck Animal Health, Madison, NJ, USA) and Meloxicam (Troy Laboratories, Glendenning, Australia)
First treatment ≥60 DOF, or fourth BRD treatment	Treated regardless of rectal temperature of CALA score, or pulled for BRD a fourth time	Ceftiofur (Excede, Zoetis Animal Health, Lincoln, NE, USA)